Computerized Neuropsychological Assessment Devices in Multiple Sclerosis: A Systematic Review

Multiple Sclerosis

Wojcik, C. M., Beier, M., et al. (2019).

Multiple Sclerosis, 25(14), 1848-1869.

<div>This systematic review investigates the psychometric properties of computerized neuropsychological assessment device batteries for identifying and monitoring cognitive impairment in individuals with multiple sclerosis (MS).</div>

No funding received



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<div>Published, peer-reviewed studies reporting psychometric data</div>

120 total studies included. 51 studies included in the quantitative synthesis.

<div>Computerized neuropsychological assessment device (CNAD) batteries failed to demonstrate adequate reliability and validity for identifying cognitive impairment in individuals with MS; however, some tests showed promise as useful screening tools or supplements to traditional assessment such as:</div> <div> <ul> <li>Subtests of the Cognitive Drug Research (CDR);</li> <li>the CogState Brief Battery (CBB);</li> <li>the NeuroTrax;</li> <li>the Central Nervous System-Vital Signs (CNSVS);</li> <li>the Computerized Symbol Digit Modalities Test (C-SDMT);</li> <li>the Processing Speed Test (PST); and</li> <li>the Computerized Speed Cognitive Test (CSCT).</li> </ul> <div>Additional research is needed to investigate ecological validity and patient-relevant outcomes of CNADs for assessing cognition in individuals with MS.</div> </div>