Are Cognitive Interventions Effective in Alzheimer's Disease? A Controlled Meta-Analysis of the Effects of Bias

Neuropsychology

Oltra-Cucarella, J., Perez-Elvira, R., et al. (2016).

Neuropsychology, 30(5), 631-652.

This meta-analysis investigates the effects of cognitive interventions (e.g., cognitive stimulation, cognitive training, cognitive rehabilitation) on cognitive outcomes in adults with Alzheimer's disease.

Not stated



Up to March 2015

Controlled studies

19

<div>Overall, cognitive intervention had low/negligible effects for functional and cognitive outcomes in individuals with Alzheimer's disease. Limitations of the paper included lack of statistical power, possible inability of broad cognitive outcome measures to detect specific cognitive change, lack of sensitivity in functional scales/questionnaires to detect small but clinically significant change, and participants taking medications that may affect cognition.&nbsp;</div>