Recommendations for Ototoxicity Surveillance for Childhood, Adolescent, and Young Adult Cancer Survivors: A Report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration With the Pancare Consortium
Lancet Oncology
Clemens, E., van den Heuvel-Eibrink, M. M., et al. (2019).
Lancet Oncology, 20(1), e29-e41.
This guideline from the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) in collaboration with the European Union-funded PanCare Consortium provides recommendations for clinicians monitoring ototoxicity in childhood, adolescent, and young adult (diagnosed at age 30 years or younger) cancer survivors.
International Late Effects of Childhood Cancer Guideline Harmonization Group; PanCare Consortium
For children, adolescents, and young adults who survived cancer, "pure tone conventional audiometry testing is recommended for survivors ≥6 years of age at 1000–8000 Hz, and additional testing with high frequency audiometry at >8000 Hz is recommended whenever equipment is available" (Evidence-based Guidelines and Expert Opinion; p. e35).
For children, adolescents, and young adults who survived cancer, those "treated with cisplatin, with or without high-dose carboplatin (>1500 mg/m²) (Level C Evidence), or head or brain radiotherapy ≥30 Gy (Expert Opinion) and their health-care providers should be aware of the risk of tinnitus. Referral to an audiologist is recommended for survivors who have symptoms of tinnitus (Expert Opinion)" (p. e35).
For children, adolescents, and young adults who have survived cancer
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<li>"Referral to an audiologist for more extensive testing is recommended for survivors <6 years of age" (Evidence-based Guidelines and Expert Opinion; p. e35).</li>
<li>"Referral to an audiologist or auditory clinic is recommended for any survivor who has symptoms suggesting hearing loss or atypical audiological test results showing a loss of more than 15 dB absolute threshold level (1000–8000 Hz)" (Expert Opinion; p. e35).</li>
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