Accuracy of the Montreal Cognitive Assessment Tool for Detecting Mild Cognitive Impairment: A Systematic Review and Meta‐Analysis
Alzheimer's & Dementia
Islam, N., Hashem, R., et al. (2023).
Alzheimer's & Dementia, 19(7), 3235-3243.
<div>This systematic review and meta-analysis investigates the clinical utility of the Montreal Cognitive Assessment (MoCA) tool for detecting mild cognitive impairment (MCI).</div>
Not stated
1995 to March 15, 2021
<div>All study designs excluding care reports</div>
13
<div>A MoCA cutoff score of 23 maximized the sensitivity (sn) and specificity (sp) for detecting MCI. This cutoff score slightly favored specificity. Summary sn and sp values were reported at the following cutoff scores:</div>
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<ul>
<li><strong>At <29: </strong>sn = 99.8%, sp = 1.1%;</li>
<li><strong>At <28: </strong>sn = 99.0%, sp = 17.5%;</li>
<li><strong>At <27: </strong>sn = 97.7%, sp = 36.5%;</li>
<li><strong>At <26:</strong> sn = 93.7%, sp= 58.8%;</li>
<li><strong>At <25:</strong> sn = 83.8%, sp = 70.8%;</li>
<li><strong>At <24: </strong>sn = 79.5%, sp = 83.7%;</li>
<li><strong>At <23: </strong>sn = 73.5%, sp = 91.3%;</li>
<li><strong>At <22: </strong>sn = 50.3%, sp = 94.0%;</li>
<li><strong>At <21:</strong> sn = 40.0%, sp = 96.3%;</li>
<li><strong>At <20:</strong> sn = 25.7%, sp = 99.4%;</li>
<li><strong>At <19: </strong>sn= 18.8%, sp = 98.6%; and</li>
<li><strong>At <18: </strong>sn = 12.0%, sp = 99.3%.</li>
</ul>
</div>
<div>Limitations to this review include a lack of investigation regarding the impact of patient characteristics on diagnostic accuracy and high or unclear risk of bias for included studies </div>
