Comparative Efficacy of Seven Nonpharmacological Interventions on Global Cognition in Older Adults With and Without Mild Cognitive Impairment: A Network Meta-Analysis of Randomized Controlled Trials
Scientific Reports
Seok, J. W., Kim, G., et al. (2024).
Scientific Reports, 14(1), 8402.
<div>This systematic review with network meta-analysis investigates the effects of non-pharmacological interventions on global cognition in adults, 55 years and older, with mild cognitive impairment (MCI). This summary highlights conclusions for interventions within the scope of speech-language pathology (i.e., cognitive training intervention).</div>
Korea Institute of Oriental Medicine; Ministry of Health & Welfare, Republic of Korea
From database inception to May 2023
<div>Randomized controlled trials</div>
61
<div style="text-align: left;">Cognitive training intervention demonstrated significant positive effects (standardized mean difference=1.383) on global cognition compared to passive controls in older adults with MCI.</div>
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<div style="text-align: left;">Limitations of this review include the small number of included studies, the insufficient service delivery data, the exclusion of studies with younger adults or multi-component interventions, and the heterogeneity of tools used to measure cognition. Additional research is needed to investigate the impact of service delivery (e.g., duration, frequency) and patient characteristics (e.g., medication use, psychological status) on cognitive outcomes in individuals with MCI.</div>
