Treatment of Chronic Refractory Cough in Adults: Focus on Neuromodulators and Other Therapeutic Modalities

Journal of Pharmacy Technology

O'Hare, C., Rahman, T., et al. (2020).

Journal of Pharmacy Technology, 36(6), 251-264.

This systematic review investigates the effects of intervention on outcomes for adults with chronic refractory cough. Only those treatments within the scope of practice of a speech-language pathologist will be summarized.

No funding received



From database inception to July 2020

Not stated

40

<div>Speech therapy was associated with positive outcomes for adults with chronic cough. Across a limited number of studies, specific improvements were seen in:</div> <ul> <li><span style="color: rgb(51, 51, 51);">cough frequency;</span></li> <li><span style="color: rgb(51, 51, 51);">cough reflex sensitivity;</span></li> <li><span style="color: rgb(51, 51, 51);">cough-related and health-related quality of life; and</span></li> <li><span style="color: rgb(51, 51, 51);">negative symptoms related to cough, breathing, voice, and upper airway functioning.</span></li> </ul> <div><span style="color: rgb(51, 51, 51);">Limitations to these findings include heterogeneity between studies and a lack of available research.&nbsp;</span></div>