Which Test Is the Best to Assess Visuo-Cognitive Impairment in Patients With Parkinson's Disease with Mild Cognitive Impairment and Dementia? A Systematic Review and Meta-Analysis
Journal of Parkinson's Disease
Liebermann-Jordanidis, H., Roheger, M., et al. (2022).
Journal of Parkinson's Disease, 12(6), 1749-1782.
This systematic review and meta-analysis explores the clinical utility of assessments of visuoperceptual, visuospatial processing, and visuo-constructive copying and drawing for discriminating between Parkinson's disease with mild cognitive impairment (PD-MCI) and Parkinson's disease dementia (PDD). While speech-language pathologists do not diagnose MCI or dementia, these findings may be applicable when assessing cognition.
Not stated
January 2008 to July 2018
All study designs
33 studies total; 19 studies included in the meta-analysis
<div>Findings demonstrated that visuo-constructive command tasks yielded the largest effect sizes (SMD = 1.06) in the differentiation between PD-MCI and PDD. However, this task incorporated fine motor, visuoperceptual, visuospatial, and cognitive abilities. <br><br>The authors noted that the following assessment tools also differentiate PD-MCI and PDD:</div>
<ul>
<li><span style="color: #333333;"><strong>the Rey–Osterrieth Complex Figure Test</strong> (SMD = 1.27);</span></li>
<li><span style="color: #333333;"><strong> the Corsi Block-Tapping Test</strong> (SMD= 1.03);</span></li>
<li><span style="color: #333333;"><strong>the Judgement of Line Orientation</strong> (Fixed Effect Model SMD = 0.67); and </span></li>
<li><span style="color: #333333;"><strong>the Clock Drawing Test</strong> (SMD = 1.54).</span></li>
</ul>
<div><span style="color: #333333;"> Limitations of this review include heterogeneity between studies and a significant risk of bias. Further research is indicated.</span></div>
