High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS) Impacts Activities of Daily Living of Patients With Post-Stroke Cognitive Impairment: A Systematic Review and Meta-Analysis
Neurological Sciences
Chen, X., Liu, F., et al. (2023).
Neurological Sciences, 44(8), 2699-2713.
This study investigates the effects of high‑frequency repetitive transcranial magnetic stimulation (HF‑rTMS) combined with routine treatment on ADLs for individuals with post-stroke cognitive impairment.
Provincial College Students Innovation and Entrepreneurship Training Program (China)
From database inception to November 2022
Randomized-controlled trials
41 in the qualitative analysis; 34 in the meta-analysis
Ten studies investigated the added effect of HF-rTMS on ADLs using the total score of the Barthel Index and showed it was significantly higher than the control group (MD =10.39, 95% CI: 7.81 to 12.96, p<0.00001). Heterogeneity of stimulation parameters was a limitation.
The total score on the Modified Barthel Index in the HF-rTMS group was significantly higher than that in the control group (MD = 9.38, 95% CI: = 7.19 to 11.58, p < 0.00001). Heterogeneity of stimulation parameters was a limitation.
Functional Independence Measures in the HF-rTMS group were higher than that in the control group (MD =4.18, 95% CI: 0.20 to 8.16, p=0.04). Heterogeneity of stimulation parameters was a limitation.