Lee Silverman Voice Treatment to Improve Speech in Parkinson's Disease: A Systemic Review and Meta-Analysis

Parkinson's Disease

Pu, T., Huang, M., et al. (2021).

Parkinson's Disease, 2021, 3366870.

This systematic review and meta-analysis investigates the effects of Lee-Silverman Voice Treatment (LSVT) on speech and voice-related outcomes in individuals with Parkinson's disease (PD).

Chengdu Medical College Foundation; Chengdu Science and Technology Bureau; Sichuan Health Commission; Sichuan Undergraduate Innovation and Startup Program (China)



From database inception to December 2021

Randomized controlled trials

10

<div>The following findings were reported following LSVT for individuals with PD:</div> <div> <ul> <li>Significantly higher sound pressure levels (SPLs) were noted following LSVT when compared to controls receiving other speech-language pathology treatment or no treatment (mean difference [MD] = 7.36 dB).</li> <li>Significantly higher SPLs were also found during vowel prolongation (MD = 13.33 dB), Rainbow Passage reading (MD = 6.67 dB) and monologues (MD = 3.93 dB).&nbsp;</li> <li>When compared to the control group, individuals receiving LSVT maintained SPL improvements at 1-6 month and 6-12 months post treatment.</li> <li>LSVT provision was associated with significantly decreased scores on the Voice Handicap Index (MD = &minus;14.60) and the Unified Parkinson&rsquo;s Disease Rating Scale-III (MD = -0.57), which is a measure of Parkinson's disease symptoms.</li> <li>LSVT had positive significant effects on speech intelligibility (MD = 16.54) and on semitone standard deviation during the Rainbow Passage reading (MD = 0.30 dB).</li> <li>No significant effects were found on semitone standard deviation during monologues.</li> </ul> <div>Heterogeneity between studies and potential for selection bias were notable limitations to this review.</div> </div>