Screening Tools for Autism in Culturally and Linguistically Diverse Paediatric Populations: A Systematic Review

BMC Pediatrics

Huda, E., Hawker, P., et al. (2024).

BMC Pediatrics, 24(1), 610.

<div>This systematic review explores the psychometric properties of autism screening tools in culturally and linguistically diverse children (i.e., individuals younger than 18 years old).&nbsp;</div>

Not stated



From database inception to October 2022

<div>Published, peer-reviewed studies</div>

51

<div><strong>The Modified Checklist for Autism in Toddlers (M-CHAT)</strong> had good overall reliability and/or validity when used with Spanish, Turkish, Chinese, Korean, French, and Arabic-speaking populations. Reported psychometrics included:&nbsp;</div> <div> <ul> <li>sensitivity = 67%-93%;</li> <li>specificity = 63%-99%;</li> <li>positive predictive value (PPV) = 14%-88%;</li> <li>negative predictive value (NPV) = 77%-100%; and&nbsp;</li> <li>internal consistency (&alpha;) = 0.76-0.9.</li> </ul> <div>Reduced reliability and/or validity were reported for th M-CHAT when used with Sinhalese, Kurdish, and Persian-speaking populations. Reported psychometrics included:&nbsp;</div> <div> <ul> <li>sensitivity = 25%-90%;</li> <li>specificity = 70%-80%;</li> <li>positive predictive value (PPV) = 5%-13%;</li> <li>negative predictive value (NPV) = 85%; and</li> <li>internal consistency (&alpha;) = 0.61.</li> </ul> </div> </div>

<div><strong>The M-CHAT, Revised with Follow-Up (M-CHAT-R/F) </strong>had good overall reliability and/or validity when used with Turkish, Spanish, Chinese, Portuguese, Serbian, Malian, Northern Soho, and Albanian-speaking populations. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 50%-100%;</li> <li>specificity = 56%-100%;&nbsp;</li> <li>PPV = 12%-100%;</li> <li>NPV = 87%-100%; and&nbsp;</li> <li>&alpha; = 0.57-0.96.</li> </ul> </div>

<div><strong>The Social Responsiveness Scale (SRS) </strong>had fair to good reliability and good to moderate validity when used with Chinese, Korean, Vietnamese, Japanese, Spanish, and Finnish-speaking populations. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 64%-100%;</li> <li>specificity = 67%-98%;&nbsp;</li> <li>PPV = 39% (one Chinese study);</li> <li>NPV = 99% (one Chinese study); and&nbsp;</li> <li>&alpha; = 0.81-0.97.</li> </ul> </div>

<div><strong>The Autism Spectrum Rating Scale (ASRS)&nbsp;</strong>had good overall validity but variable reliability when used with Chinese-speaking populations in China. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 89%-94%;</li> <li>specificity = 77%-85%;&nbsp;</li> <li>PPV = 39%;</li> <li>NPV = 99%; and&nbsp;</li> <li>&alpha; = 0.59-0.93.</li> </ul> </div>

<div><strong>The Social Communication Questionnaire (SCQ) </strong>had good to high reliability and validity when used with Arabic, Greek, Malian, and Chinese-speaking populations. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 71%-96%;</li> <li>specificity = 72%-98%;&nbsp;</li> <li>PPV = 73% (one Malian study);</li> <li>NPV = 70% (one Malian study); and&nbsp;</li> <li>&alpha; = 0.92.</li> </ul> </div>

<div><strong>The Quantitative Checklist for Autism in Toddlers (Q-CHAT) </strong>had acceptable reliability and validity when used with Italian and Serbian-speaking populations. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 83% (Italian) and 96% (Serbian);</li> <li>specificity = 78% (Italian) and 82% (Serbian);&nbsp;</li> <li>PPV = 39% (one Serbian study);</li> <li>NPV = 99% (one Serbian study); and&nbsp;</li> <li>&alpha; = 0.68-87.</li> </ul> </div>

<div>One study found that the&nbsp;<strong>Childhood Autism Spectrum Test (CAST) </strong>had good reliability and acceptable validity when used with Spanish-speaking populations in Spain. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 84%;</li> <li>specificity = 93%;&nbsp;</li> <li>PPV = 63%; and</li> <li>&alpha; = 0.83.</li> </ul> <div>Two studies reported good reliability for Chinese-speaking individuals in China (weighted kappa = 0.53, theta = 0.89).</div> </div>

<div>One study found that the <strong>Autism Spectrum Quotient-Child (AQ-C) </strong>had good reliability and validity when used with Chinese-speaking populations in China. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 94%;</li> <li>specificity = 88%; and</li> <li>&alpha; = 0.77.</li> </ul> </div>

<div>Across two studies, the <strong>Indian Autism Screening Questionnaire/ Indian Scale for Assessment of Autism (IASQ/ISAA)</strong> had good reliability and high validity when used with Hindi-speaking individuals in India. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 97%;</li> <li>specificity = 81%;</li> <li>PPV = 63%;&nbsp;</li> <li>NPV = 99%; and</li> <li>&nbsp;&alpha; = 0.93.</li> </ul> </div>

<div>One study found that the&nbsp;<strong>Autism Behaviour Checklist (ABC) </strong>had moderate sensitivity but poor specificity when used with Mandarin Chinese-speaking populations in China. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 80%;</li> <li>specificity = 59%;&nbsp;</li> <li>PPV = 93%; and</li> <li>NPV = 32%.</li> </ul> </div>

<div>One study found that the&nbsp;<strong>Autism Spectrum Screening Questionnaire (ASSQ) </strong>had fair validity when used with Finish-speaking populations in Finland. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 89%;</li> <li>specificity = 82%;&nbsp;</li> <li>PPV = 62%; and</li> <li>NPV = 96%.</li> </ul> </div>

<div>One study found that the&nbsp;<strong>Hiva</strong> screening tool had high validity and poor validity when used with Kurdish and Persian-speaking populations in Iran. Reported psychometrics included:</div> <div> <ul> <li>sensitivity = 100%;</li> <li>specificity = 97%;&nbsp;</li> <li>PPV = 38%; and</li> <li>&alpha; = 0.58.</li> </ul> </div>

<div>One study found that the <strong>Toddler Autism Screening Questionnaire (TASQ) </strong>had high sensitivity (100%) and specificity (97%) when used with Taiwanese-speaking populations in Taiwan.</div>