The Effect of Combined Cognitive Intervention and Physical Exercise on Cognitive Function in Older Adults With Mild Cognitive Impairment: A Meta-Analysis of Randomized Controlled Trials
Aging Clinical and Experimental Research
Meng, Q., Yin, H., et al. (2022).
Aging Clinical and Experimental Research, 34, 261-276.
This systematic review and meta-analysis compares the effects of cognitive intervention to the effects of: physical exercise, a combination of cognitive intervention and physical exercise, or no intervention on cognitive function in adults, 50 years and older, with mild cognitive impairment (MCI).
Health and Family Planning Committee of Jilin Province (China); Education Department of Jilin Province (China)
From database inception to February 2021
Randomized controlled trials
16
<div>Cognitive interventions did not improve global cognition in older adults with MCI when compared to physical exercise alone or combined treatments of cognitive intervention and exercise. Cognitive interventions, physical interventions, and combined treatments had a greater effect on global cognition when compared to no treatment. Specific findings included:</div>
<ul>
<li><span style="color: #333333;">Cognitive intervention had comparable results for memory when compared to combined interventions, with b</span><span style="color: #333333;">oth interventions demonstrating a greater effect on memory compared to no intervention. </span></li>
<li><span style="color: #333333;">Combined treatments demonstrated greater effects on executive function and attention (SMD = 0.28)</span><span style="color: #333333;"> compared to cognitive intervention alone. </span><span style="color: #333333;">Both interventions demonstrated greater effects on executive function and attention compared to no intervention.</span></li>
</ul>
