A Systematic Review of Patient-Reported Outcome Measures in Head and Neck Cancer Surgery

Otolaryngology—Head & Neck Surgery

Pusic, A., Liu, J. C., et al. (2007).

Otolaryngology—Head & Neck Surgery, 136(4), 525-535.

This systematic review investigates the validity of patient-reported outcome measures for assessing quality of life, speech, swallowing, or voice in individuals with head and neck cancer undergoing surgery.

Not stated



From 1966 to March 2006

Not further specified

12 outcome measures; Number of studies was not stated

<div>One instrument was included in this review that pertained to the measurement of swallowing, the MD Anderson Dysphagia Inventory (MDADI). The MDADI is a "20-item five-point Likert questionnaire that assesses dysphagia in three domains (functional, emotional, physical) in head and neck cancer patients" (p. 531). "Psychometric testing demonstrated good test-retest reliability (functional, 0.88; emotional, 0.88; physical, 0.86) and internal consistency reliability (overall Cronbach alpha, 0.96)" (pp. 531-532). "Concurrent validity was assessed by comparison with the PSS and found to be moderate (Spearman correlation, 0.47 to 0.61). Convergent validity was demonstrated with the physical functioning subscale of the SF-36 (Spearman correlation, 0.40) and divergent validity with the emotional functioning subscale of the SF-36 (Spearman correlation, 0.36)" (p. 532).</div>

<div>One instrument was included in this review that pertained to the measurement of speech and voice, the Linear Analogue Self-Assessment (LASA). The LASA questionnaire for assessment of head and neck cancer "investigates 16 areas of voice quality through the use of eight symptom and eight function scales" (p. 531). "Test-retest reliability was greater than 0.7 for 12 of 16 scales and responsiveness showed statistically significant changes over time in three of the eight symptom scales and for five of the eight function scales. A high correlation between LASA score and physician perspective on voice quality was noted in a subsequent study, with test-retest reliability &gt; 0.7" (p. 531).</div>

<div>Nine general quality of life instruments were included in this review. "The&nbsp;EORTC H&amp;N 35&nbsp;[European Organization for Research &amp; Treatment of Cancer H&amp;N 35], the HNQOLQ&nbsp;[University of Michigan H&amp;N Quality of Life Questionnaire], and the HNCI [Head and Neck Cancer Inventory] would appear to be particularly robust questionnaires that have undergone thorough development and validation and address many important aspects of the patient experience" (p. 533).</div>