A Comprehensive Approach to Rehabilitation Interventions in Patients With Angelman Syndrome: A Systematic Review of the Literature
Neurology International
Sommese, M., & Corrado, B. (2021).
Neurology International, 13(3), 359-370.
This systematic review investigates rehabilitation for individuals with Angelman syndrome. Only those treatments within the scope of practice of a speech-language pathologist will be summarized.
No funding received
From January 2001 to December 2020
Published studies of any design
15
<div>Augmentative and alternative communication (AAC) had mixed effects for individuals with Angelman syndrome. </div>
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<li>Gesture instruction generally improved communication across three studies.</li>
<li>Use of a picture exchange communication system (PECS) resulted in increased request responses and reduced challenging behaviors within one study. </li>
<li>Multimodal AAC interventions resulted in mixed outcomes across five studies, with three studies demonstrating positive effects and two studies demonstrating variable effects. </li>
</ul>
<div>Limitations to this review include an overall lack of research, small sample sizes, and heterogeneity between studies.</div>
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