Treatments for Hearing Loss in Osteogenesis Imperfecta: A Systematic Review and Meta-Analysis on Their Efficacy
Scientific Reports
Ugarteburu, M., Cardoso, L., et al. (2022).
Scientific Reports, 12(1), 17125.
This systematic review and meta-analysis investigates the effects of treatment on hearing outcomes for individuals with osteogenesis imperfecta.
National Science Foundation
From database inception to November 2020
Peer-reviewed studies
13 studies included in the systematic review; 12 studies included in the meta-analysis
Findings from the systematic review indicate improved speech perception with cochlear implants for individuals with osteogenesis imperfecta. Improved hearing thresholds with bone-anchored hearing aids and implantable hearing aids were additionally noted for this population. Success was limited by bone fragility and high vascularity. The meta-analysis showed stapes surgeries have a low success rate due to atrophy and fracture of the ossicles. Limitations to this review include the small number of studies due to the rarity of this condition.
