Curbing the Cough: Multimodal Treatments for Neurogenic Cough: A Systematic Review and Meta-Analysis
Laryngoscope
Wamkpah, N. S., Peterson, A. M., et al. (2022).
Laryngoscope, 132(1), 107-123.
This meta-analysis investigates procedural, pharmacologic, and non-pharmacologic treatments in individuals with neurogenic cough.
No funding received
Database inception to February 2020
Clinical trials; cohort studies; case-control studies; case series with more than 10 subjects.
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<div>Findings demonstrated that speech therapy resulted in improved quality of life and cough severity (effect size = 0.86) in adults with chronic cough. Compared to non-scope treatments, speech therapy had the greatest proportion of patients with improved cough (86%) and was not associated with adverse events. Of note, trigger reduction therapy and breath training therapy led to lower post-treatment cough severity index than cough suppression techniques. <br><br>Limitations to this review included a lack of direct comparisons between groups, low-to-intermediate quality evidence, and high heterogeneity. Further research is warranted.</div>
