Diagnostic Accuracy of the Family Confusion Assessment Method for Delirium Detection: A Systematic Review and Meta-Analysis
Journal of the American Geriatrics Society
Zhou, C., Wang, H., et al. (2024).
Journal of the American Geriatrics Society, 72(3), 892-902.
<div>This systematic review and meta-analysis investigates the diagnostic accuracy of the Family Confusion Assessment Method (FAM-CAM) for delirium detection. Of note, although speech-language pathologists (SLPs) do not diagnose delirium, SLPs may administer delirium screening tools as part of a multidisciplinary effort to prevent and manage delirium.</div>
Huazhong University of Science and Technology (China); 2023–2024 General Program of Health Commission of Hubei Province (China)
From January 1988 to December 2022
<div>Cross-sectional, retrospective, or prospective design studies</div>
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<div>Meta-analysis revealed the following psychometrics for the FAM-CAM when used to detect delirium in adults:</div>
<div>
<ul>
<li>pooled sensitivity of 0.74;</li>
<li>pooled specificity of 0.91;</li>
<li>positive likelihood ratio of 8.27;</li>
<li>negative likelihood ratio of 0.28; and</li>
<li>area under the curve of 0.91.</li>
</ul>
<div>Meta-regression of the FAM-CAM showed:</div>
<div>
<ul>
<li>no significant differences in sensitivity or specificity based on reference standard (either the DSM or validated tools) and</li>
<li>setting had a significant impact on pooled specificity. In the intensive care unit (ICU), the pooled specificity estimate was 0.85 and in non-ICU settings, the pooled specificity was 0.93.</li>
</ul>
</div>
<div>Limitations to this review included the small number of included studies, heterogeneity of reference standards among the included studies, and potential publication bias due to the exclusion of gray literature.</div>
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