The Effectiveness of Memory Remediation Strategies After Traumatic Brain Injury: Systematic Review and Meta-Analysis

Annals of Physical and Rehabilitation Medicine

Lambez, B., & Vakil, E. (2021).

Annals of Physical and Rehabilitation Medicine, 64(5), 101530.

This systematic review with meta-analysis investigates the effects of injury severity on memory remediation intervention outcomes in individuals with traumatic brain injury (TBI).

Israeli Ministry of Defense, Rehabilitation Department



From January 1980 to January 2020

Randomized control trials and non-randomized control trials with pre- and post-intervention measures.

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Memory remediation interventions improved memory impairments in individuals with TBI. Interventions demonstrated the greatest effects in individuals with moderate-severe TBI (0.65; <em>df</em>=11; 95% CI=0.81 to 0.91; <em>p</em>&lt;0.05) compared to individuals with mild-moderate TBI severity (0.61; <em>df</em>=5; 95% CI=-0.06 to 0.91; <em>p</em>&lt; 0.05). Mixed internal and external cognitive interventions showed the largest positive effects on cognitive memory for both individuals with mild-moderate severity (0.79; <em>df</em>=2; 95% CI=0.13 to 1.06) and moderate-severe TBI (0.81; <em>df</em>=1; 95% CI=0.35 to 1.27). Limitations include the small number of included studies and the heterogeneity of participant characteristics. Additional randomized clinical trials investigating injury severity categories are warranted.