Addressing Cognitive Impairment Following Stroke: Systematic Review and Meta-Analysis of Non-Randomised Controlled Studies of Psychological Interventions

BMJ Open

Merriman, N. A., Sexton, E., et al. (2019).

BMJ Open, 9(2), e024429.

This meta-analysis examines the effectiveness of psychological interventions aimed at improving general cognitive function in individuals post-stroke.

Health Research Board of Ireland Interdisciplinary Capacity Enhancement Award



Up to February 2017

Non-randomized studies; quasi-randomized controlled trials

20

<div>Neuropsychological interventions (e.g., computerized interventions, behavioral interventions, strategy training, goal management training) may be effective for improving overall cognitive function post-stroke.</div> <div> <div> <ul> <li>Small effects on cognition were noted across controlled studies (Hedges' g = 0.38) with greatest benefit noted on attention. Improvements in executive function, processing speed, memory and&nbsp; IQ were non-significant.&nbsp;</li> <li> <div>Positive effects on cognition were also noted across pre-post studies (Hedges' g = 0.5) with the greatest benefits reported in attention, memory and global cognition domains.</div> </li> <li> <div>Non-significant results were found in executive function, instruments and activities of daily living, IQ, subjective memory, perceptual reasoning, and quality of life.&nbsp;</div> </li> </ul> <div>Given the low methodological quality of included studies and risk of bias, further research in this area is warranted.&nbsp;</div> </div> </div>