Systematic Review and Meta-Analysis of a New Active Transcutaneous Bone Conduction Implant
Laryngoscope
Key, S., Mohamed, N., et al. (2024).
Laryngoscope, 134(4), 1531-1539.
<div>This systematic review and meta-analysis investigates the pooled functional gain for Osia, an active transcutaneous bone conduction implant. </div>
Not stated
Database inception to September 20, 2022
<div>Randomized controlled trials, cohort studies, case-control studies, and case series with more than 5 patients</div>
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When compared to unaided hearing, findings demonstrated a pooled overall mean functional gain of 35.0 dB sound pressure level (SPL; 95% CI= 29.12-40.97) following Osia implantation for all types of hearing loss. Pooled functional gain for conductive/mixed hearing loss was 37.7 dB SPL (95% CI= 26.1-49.3). The pooled functional gain for single-sided deafness could not be calculated due to a small patient cohort. Mixed findings were noted for patient-reported outcomes measures (PROMs). While there is a trend toward improvements in speech receptiveness threshold and signal to noise ratio when compared with baseline hearing, data for these outcomes could not be pooled for meta-analysis due to heterogeneity in study designs. Rates of early complication rates for Osia implantation were comparable to other transcutaneous implants for explantation (0.11%, 95% CI= 0.00%-1.90%) and wound infection rate (1.92%, 95% CI= 0.00%-6.17%). Additional research is indicated due to limited, low quality evidence.
