A Systematic Review and Meta-Analysis of Studies on Screening for Mild Cognitive Impairment in Primary Healthcare
BMC Psychiatry
Karimi, L., Mahboub-Ahari, A., et al. (2022).
BMC Psychiatry, 22(1), 97.
This systematic review and meta-analysis investigates the test performance of screening tools used in primary care settings for the early diagnosis of cognitive impairment in adult populations with suspected mild cognitive impairment or mild dementia.
Tabriz University of Medical Sciences (Iran)
January 2012-November 2022
All study designs
21
Twelve cognitive screening tools were examined across 21 studies, the majority of which included the Mini-Mental State Examination (MMSE). MMSE pooled sensitivity = 0.73 (95% CI 0.57–0.90) and pooled specificity = 0.83 (95% CI 0.75—0.90). Pooled analysis of other screening instruments was not completed due to high heterogeneity of included studies. However, overall findings revealed that the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), the Ascertain Dementia 8-item (AD8) and the General Practitioner Assessment of Cognition (GPCOG) were equal to or had better diagnostic accuracy (i.e., sensitivity and specificity) compared to the Mini-Mental State Examination (MMSE).
